Microdosing Information

Overview

The term "Micro-dose" was coined in 2011 by Dr James Fadiman in the release of his book The Psychedelic Explorers Guide (which we highly recommend). He Defined it as approximately 1/10th of a hallucinogenic dose, or between 100 and 250mg for Psilocybin Mushrooms, and recommended it be taken once every 3 days. Albert Hoffman (the inventor of LSD) has also been quoted suggesting that taking a minuscule amount of a Psychedelic substance could have positive impact on mental health and physical functioning.

These two, along with many other researchers and psychonauts (Like Paul Stamets and Michael Pollan) are accredited, well respected individuals who have been exposed to the monumental amount of anecdotal evidence that Micro-dosing benefits mood, anxiety, focus, creativity and empathy. Here is a succinct informational interview from the Joe Rogan Experience podcast #1385 with Paul Stamets that epitomizes this kind of evidence, anecdotal but by no means invaluable.

While the exponentially increasing anecdotal evidence is vast, it is not grounds for a conclusive scientifically backed statement or fact. However this will not be the case for long. Multiple studies have already been conducted (albeit with small sample sizes), and many are cited below. Moreover numerous accredited universities like Harvard, Stanford, University of Toronto, and John Hopkins are in the process of conducting human clinical trials using Psilocybin to treat a variety of psychological conditions including depression, anxiety, PTSD, OCD, addiction, and eating disorders.

Universities studying Psilocybin
*Universities currently conducting human Psilocybin trials*

 

One Study at the University of Bergen found that the respondents reported mostly positive effects, including improved mood, cognition, and creativity. Furthermore, these effects “often served to counteract symptoms especially from conditions of anxiety and depression.”

Not everyone found the experience smooth or valuable though. There were some reports of difficulties with Micro-dosing, and some did not consider it to be worth continuing after giving it a try.
 
Another notable study published in the journal of Psychopharmacology investigated the effects that Micro-dosing psilocybin has on mental cognition in healthy adults. During a Micro-dosing event organized by the Dutch Psychedelic Society, researchers tested 38 volunteers with a set of creativity-related problem-solving tasks and a standard assessment of fluid intelligence that were administered before and after the participants Micro-dosed.
   
The findings from this study indicated that microdosing psilocybin has the potential to enhance creativity (specifically with regard to convergent and divergent thinking) but likely does not increase overall intelligence.

 

Dosing Schedule

The two most prominent Micro-dosing schedules (which are often used by studies and trials) are the Stamets protocol and the Fadiman Protocol.
 
Fadiman protocol - 1 Day dosing followed by 2 Days off
Stamets Protocol - 4 Days dosing followed by 3 Days off
 
We encourage all Micro-dose users to register for the Quantified Citizen project. It is a free app that allows you to track your Micro-dosing regimen and anonymously submit the data for researchers to utilize. In addition to the app it is greatly appreciated if you write a few notes to yourself about how your day went.
Consider, for example, the amount of work you did, how productive or creative it was, and the level of ease or discomfort you felt. Notice any changes in how you are relating to others. Notice any differences from normal in mood, food, physical strength, or symptoms of any condition."
    
This App and recording data regarding microdosing is a crucial initiative due to the fact that most studies conducted around the topic of Micro-dosing thus far have had small sample sizes. Preliminary findings from these studies are overwhelmingly positive, however scientifically concrete evidence is needed from larger meta-analyses. Quantified Citizen seeks to aggregate this information from the public.

 

Conclusion

In Conclusion the field of research around psychedelics is still in its infancy. Results from preliminary studies have shown promise for the safety and efficacy of microdosing psychedelics and future research is primed by the credentials of many institutions who have chosen to involve themselves in pioneering this field. The coming years will prove enlightening for citizens and scientists alike who want to know more about the science behind microdosing.

 

We have gathered some resources regarding Micro-dosing, if you have any additional questions, do not hesitate to contact us!
   
 
Check out these Scholarly Peer reviewed articles about Psilocybin